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Methylation and Inflammation Resolution

Methylation and Inflammation Resolution

PRECISION METHYLATION AND INFLAMMATION RESOLUTION

A Functional Genomics Approach
Move beyond an isolated MTHFR result.

Read methylation as a functional pathway, not a single genetic finding.

Methylation depends on the flow of folate and B12 through an interconnected cycle, the availability and use of methyl groups, and what the patient’s biomarkers and phenotype show today. This course teaches you to interpret methylation capacity alongside homocysteine, folate, B12, COMT activity, hormone clearance, and inflammation resolution so you can distinguish genetic tendency from current physiology.

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What you’ll learn

  • Follow the methylation cycle. Understand the flow from folate and B12 to homocysteine, methionine, and SAMe.
  • Interpret the pattern, not one variant. Examine SHMT1, MTHFR, MTR, and MTRR across folate-side, B12-side, and mixed presentations.
  • Connect methylation with clearance. Understand COMT’s role in catechol estrogen and catecholamine metabolism.
  • Bring biomarkers into the interpretation. Integrate genotype with homocysteine, B12, folate, symptoms, and clinical phenotype.
  • Translate the findings carefully. Use the pathway to identify meaningful next steps, safety considerations, and when additional evaluation is appropriate.

Turn methylation data into a clearer clinical picture.

Cost: $299

Included: A physical Quicksilver kit curated for this course

Format: Online and self-paced

Start with: Foundations of Functional Genomics, free

Work through the methylation interpretation framework, apply it to clinical cases, and check your understanding through a case-based assessment. The course includes folate- and B12-side pathway tools, genotype-to-phenotype interpretation, COMT integration, and an inflammation-resolution framework.


Follow methylation into neurochemistry and vascular health.

Methylation connects hormone clearance with catecholamine metabolism, inflammatory signaling, and vascular function. Continue through the certification to understand how those relationships influence the priorities you identify for each patient.

The Clinical Genomics Certification is $1,999 and includes all eight modules, a combined Quicksilver kit, practice implementation support, and three months of educational chatbot access.

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